Primer premier 6 keygen5/25/2023 ![]() In addition, a comprehensive analysis of nine identified RBPs showed that most of them were related to the OS of HNSCC patients, and three of them ( CELF2, EZH2, and SIDT1) were differentially expressed in HNSCC and control tissues at the protein level. The area under the ROC curve (AUC) in the training and testing groups was significant (3-year AUC, 0.735 vs 0.796 5-year AUC, 0.821 vs 0.804). Further analysis showed that the overall survival rate in the high-risk group was lower than that in the low-risk group. ![]() Finally, a prognostic model containing nine RBPs ( CELF2, CPEB1, DDX39B, EIF3L, EZH2, KHDRBS3, RNASE10, RNASE3 and SIDT1) was produced. We obtained 502 tumors and 44 normal samples from the TCGA database, among which 190 differentially expressed RBPs were screened. ![]() Evidence shows that defects in RNA-binding proteins (RBPs) are closely related to the occurrence and development of HNSCC.
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